Allergic reaction - drug (medication)
    
Share |
 
  

Diseasereference.net - Comprehensive articles covering over 1,700 topics. The articles are organized by the disease, condition overview, symptoms, treatment, and prevention.


Drugs search, click the first letter of a drug name:
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | 1 | 2 | 3 | 4 | 5 | 6 | 8 | 9

Terms search, click the first letter of a term name:
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Online medical services

Medical dictionary Med-Terms.net is a searchable dictionary of medical terms from medicine and related fields. Search for medical terms with our medical dictionary.

Drugs & Medications Search our drug database for comprehensive prescription and patient information on 24,000 drugs online. Drugspedia.net - The Internet Drug Index for prescription drugs and medications.

PMS blog Premenstrual syndrome (PMS), PMS headache


Blue waffles disease, blog. Blue waffle infection, blue waffle disease pictures.

  

 

Disease Reference

Click on the first letter in the disease name:

| 4 | 5 | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z



     

Allergic reaction - drug (medication)

Definition

Drug allergies are a group of symptoms caused by allergic reaction to a drug (medication).

Alternative Names

Allergic reaction - drug (medication)

Causes

In general, adverse reactions to drugs are not uncommon, and almost any drug can cause an adverse reaction. Reactions range from irritating or mild side effects such as nausea and vomiting to life-threatening anaphylaxis.

True drug allergies occur when there is an allergic reaction to a medication. The first time you take the drug, your immune system launches an incorrect response against a substance that is harmless in most people. The second or next time you take the drug, an immune response occurs, and your body produces antibodies and histamine.

Most drug allergies cause minor skin rashes and hives. However, other symptoms occasionally develop and life-threatening acute allergic reaction involving the whole body can occur. Serum sickness is a delayed type of drug allergy that occurs a week or more after exposure to a medication or vaccine.

Penicillin and related antibiotics are the most common cause of drug allergies. Other common allergy-causing drugs include:

  • Sulfa drugs
  • Anticonvulsants
  • Insulin preparations (particularly animal sources of insulin)
  • Local anesthetics such as Novocain
  • Iodine (found in many x-ray contrast dyes)

Some drug reactions are considered idiosyncratic. This means the reaction is an unusual effect of the medication. For example, aspirin can cause nonallergic hives or trigger asthma. Only a small number of these reactions are allergic in nature. Many individuals may confuse an uncomfortable but not serious side effect of a medicine, such as nausea, with a true drug allergy, which can be life threatening.

Symptoms

  • Hives (common)
  • Skin rash (common)
  • Itching of the skin or eyes (common)
  • Wheezing
  • Swelling of the lips, tongue, or face
  • Anaphylaxis, or severe allergic reaction (see below)

Symptoms of anaphylaxis include:

  • Difficulty breathing with wheeze or hoarse voice
  • Hives over different parts of the body
  • Fainting, light-headedness
  • Dizziness
  • Confusion
  • Rapid pulse
  • Sensation of feeling the heart beat (palpitations)
  • Nausea, vomiting
  • Diarrhea
  • Abdominal pain or cramping

Exams and Tests

An examination of the skin and face may show hives, rash, or angioedema (swelling of the lips, face, or tongue). Decreased blood pressure, wheezing, and other signs may indicate an anaphylactic reaction.

Skin testing may confirm allergy to penicillin-type medications. Testing may be ineffective (or in some cases, dangerous) for other medications. A history of allergic-type reaction after use of a medication is often considered proof enough of drug allergy -- no further testing is required. The same applies to other substances that are not considered drugs but are used in hospitals, such as x-ray contrast dyes.

Treatment

The treatment goal is relief of symptoms and preventing a severe reaction.

Treatment may include:

  • Antihistamines to relieve mild symptoms such as rash, hives, and itching
  • Corticosteroids applied to the skin
  • Bronchodilators such as albuterol to reduce asthma-like symptoms (moderate wheezing or cough)
  • Epinephrine by injection to treat anaphylaxis

The offending medication and similiar drugs should be avoided. Make sure all your health care providers -- including dentists and hospital personnel -- know about any drug allergies that you or your children have.

Identifying jewelry or cards (such as Medic-Alert or others) may be recommended.

Occasionally, a penicillin allergy responds to immunotherapy. Increasing doses of a medicine are given to improve a person's tolerance of the drug. This should only be done by an allergist.

Outlook (Prognosis)

Most drug allergies respond readily to treatment. A few cases cause severe asthma, anaphylaxis, or death.

Possible Complications

  • Asthma
  • Anaphylaxis (life-threatening)
  • Death

When to Contact a Medical Professional

Call your health care provider if you are taking a medication and seem to be having a reaction to it.

Go to the emergency room or call the local emergency number (such as 911) if you have difficulty breathing or develop other symptoms of severe asthma or anaphylaxis. These are emergency conditions.

Prevention

There is no known way to prevent development of a drug allergy.

If you have a known drug allergy, avoiding the medication is the best way to prevent an allergic reaction. You may also be told to avoid similar medicines. For example, if you are allergic to penicillin, you should also avoid amoxicillin or ampicillin.

In some cases, a doctor may approve use of a drug that causes an allergy if you are pre-treated with corticosteroids (such as prednisone) and antihistamines (such as diphenhydramine). Do not try this without a doctor's supervision.

Adkinson NF Jr. Middleton's Allergy: Principles and Practice. 6th ed. Chapter 92. Philadelphia, Pa: Mosby; 2003.

Email to a Friend


Your Name:

Friend's Email:



More about Allergic reaction - drug (medication) - Drugs.com
   Allergic reaction - drug (medication)
Ankyloglossia
Acute granulocytic leukemia
Alopecia areata
Anemia - sickle cell
Acanthosis nigricans
Acute bacterial tracheitis
Acute HIV infection
Atypical pneumonia
Craniosynostosis



 
  
Medical dictionary | Natural mosquito repellents | Dust mites pictures | Prescription Drug Information | new 401k rules | Hyperkeratosis pilaris treatment
© Copyright by Diseasereference.net 2006-2007. All rights reserved