Hypersplenism Definition Hypersplenism is a condition in which the spleen is overactive. It can be caused by tumors, anemia, malaria, tuberculosis Symptoms include an enlarged spleen that is often accompanied by a low level of one or more types of blood cells. The enlarged spleen can cause stomach pain on the left side, as well as a premature feeling of fullness after eating. Ferri FF. Ferri's Clinical Advisor 2007: Instant Diagnosis and Treatment. 9th ed. Philadelphia, Pa: Mosby; 2007:443. Hoffman R, Benz Jr. EJ, Shattil SJ, et al., eds. Hematology: Basic Principles and Practice. 4th ed. Philladelphia, Pa: Churchill Livingston; 2005:711-12. |