Post-splenectomy syndrome

Definition

Post-splenectomy syndrome is a group of symptoms and signs that frequently occur after surgical removal of the spleen (splenectomy).

These include:

• Thrombocytosis (increased platelet count, which can cause blood clots)
• Destruction of red blood cells
• Increased susceptibility to severe infections, especially with organisms such as Streptococcus pneumoniae

Alternative Names